Lead Product Designer

At Unlearn, our purpose is to advance artificial intelligence (AI) to eliminate trial and error in medicine. We are innovating advanced machine learning methods to leverage generative AI in forecasting patient outcomes, starting with the domain of clinical trials. We produce AI-generated digital twins of individual trial participants, enabling smaller and more efficient clinical trials to bring effective medicines to patients sooner.

Our innovative work in AI today will reinvent how AI is applied in medicine tomorrow — and we have a top secret plan for how to get there. We won’t be able to achieve this mission just by applying technologies created by others; the future must be invented.

Unlearn is a technology company, not a biotech company. We use computers, not pipettes. We make and use software, we don’t discover or make drugs. We believe that AI will define the future of medicine, and we aren’t deterred by naysayers or skeptics. 

We come from a variety of backgrounds ranging from machine learning to marketing—but regardless of where we come from, Unlearners share some common traits:

• Unlearners are ambitious; we aren’t intimidated by big, challenging goals. 

• Unlearners are disciplined experimenters; we break down our big goals into smaller chunks and meet as often as necessary to track our velocity and iterate quickly. 

• Unlearners are gritty; we never give up, setbacks just make us try harder.

• Unlearners are receptive to new ideas; in fact, we hate being stuck with the status quo

• Unlearners are storytellers; sharing information with each other and with the world is super important, too important to be boring.  And, last but not least,

• Unlearners are team-oriented; we put the mission first, the company second, the team third, and individuals last.

Headquartered in San Francisco, Unlearn was founded in 2017 by a team of world-class machine learning scientists.  We have raised venture capital from top tier investors such as Altimeter, Insight Partners, Radical Ventures, 8VC, DCVC, and DCVC Bio, and recently completed our $50 million Series C in January 2024.

If our purpose and culture resonate with you, we invite you to apply.

We’re looking for a Lead Product Designer to shape the future of design at Unlearn. In this role, you’ll guide the design direction for our Unlearn Platform - the suite of products that enables our biopharma customers to use our digital twin technology and AI to continually inform and accelerate critical decisions, enabling them to deliver drugs to patients more quickly.

As our most senior individual contributor, you’ll balance hands-on design work with leadership and mentorship responsibilities. You’ll partner closely with product, engineering, machine learning, and research teams to define user experiences that are both elegant and deeply technical. You’ll also play a key role in scaling our design culture, systems, and processes as Unlearn grows.

• Lead design strategy and execution for Unlearn’s core platform and AI-powered products.

• Drive end-to-end design, from discovery and concept through to prototyping, validation, and delivery.

• Partner with PMs, engineers, and ML researchers to define product direction and advocate for design excellence.

• Mentor other designers, guiding their craft, process, and communication.

• Help shape Unlearn’s design function: processes, rituals, and best practices that support velocity and quality.

• Lead customer research and usability testing to ensure designs are grounded in real-world user needs.

• Evangelize the role of design across the company, helping teammates understand how thoughtful UX drives business and scientific outcomes.
  

Maker & Leader. You love designing, but you also love mentoring and scaling design impact across a team.

Crafts(wo)man. You hold yourself to a high bar for design excellence, but you also know when to ship, learn, and iterate.

Systems Thinker. You see patterns, workflows, and connections where others see complexity, and you design frameworks that scale.

User-Centered. You start with empathy and advocate for user needs while balancing business goals and technical realities.

Curious & Intentional. You ask “why” relentlessly, think deeply about details, and can clearly articulate the rationale behind every decision.

Collaborative. You thrive in multidisciplinary teams, integrating input from research, data science, and engineering.

Resilient & Adaptable. You stay calm and focused through churn, ambiguity, and iteration.

Design Evangelist. You’re excited to help others understand and appreciate design’s value in a high-velocity, research-driven environment.

• 7+ years of experience in product design, including leadership of complex, data-rich products.

• Strong portfolio demonstrating end-to-end product thinking, from insight to polished execution.

• Proven experience shipping 0→1 products in startup or high-growth environments.

• Deep experience designing complex workflows or analytic tools (bonus for healthcare, science, or data visualization).

• Skilled in Figma and modern prototyping tools.

• Excellent communication and storytelling skills; able to influence across functions and levels.

• Experience mentoring or leading designers.

• Knowledge of biopharma, biotech, or clinical trial software is a plus but not required.

• Case studies that clearly describe goals, research insights, constraints, concepts, tradeoffs, and impact.

• Evidence of both craft and systems thinking, not just what you designed, but how and why.

• Work that demonstrates complex problem-solving (not just visual polish).

• A range of consumer and enterprise examples, especially those involving data or workflows.
  

• Mission-driven company building the future of AI in biopharma and beyond.

• Opportunity to shape design culture and practice at a pivotal growth stage.

• Close collaboration with world-class engineers, machine learning scientists, and product leaders.

• Competitive compensation, meaningful equity, and comprehensive benefits.

The following benefits and perks are for full time roles only.

• Generous equity participation

• 100% company-covered medical, dental, & vision insurance plans

• 401k plan with matching

• Flexible PTO plus company holidays

• Annual company-wide break December 24 through January 1

• Commuter benefits

• Paid Parental Leave

• Support for H1B, TN, and E-3 Visa change of employer transfers

Unlearn is an equal opportunity employer. 

At Unlearn, we are committed to building a diverse and inclusive workplace, because inclusion and diversity are essential to achieving our mission. If you’re excited about this role, and your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply nevertheless.