Director, Global Commercial Leader, Early Heme Pipeline

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description:

BeOne, a global oncology company, has produced a robust pipeline of New Molecular Entities (NMEs) with potential to change the standard of care across numerous disease areas. More than 10 additional NMEs can be expected from the Discovery organization in 2026, adding to an already comprehensive set of molecules spanning multiple modalities and which are currently in early- and late-stage Clinical Development.  This pipeline maturation has driven One growth and generated challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly share our passion to fight cancer and our commitment to serve patients wherever they reside.

As the Director/Associate Director, Global Commercial Leader, Early Hematology Pipeline, you will play a critical leadership role in our newly formed Global Commercial Strategy and Operations team. You will be responsible for overlaying a commercial perspective that guides our Research and Development efforts in the Hematology therapeutic area, with efforts to help create differentiated Target Product Profiles (TEPs/TPPs), sizing commercial opportunities, generating insights into patient and physician unmet needs, and guiding investment into the most productive and impactful areas. You will serve as the Commercial voice on the Early Development Teams (EDTs) helping to ensure a robust evidence package that meets the needs of various Regional stakeholders including Regulatory and Reimbursement bodies around the globe. You will also play a leading role in helping to develop our pan-Hematology strategy.

This role requires comprehensive knowledge of the Hematology therapeutic area landscape, a deep understanding of the drug development process, and a keen business acumen. This role will serve as the primary Commercial lead into R&D/ Clin Dev governance decisions. The ideal candidate brings deep Hematology market knowledge, strong scientific fluency, and a track record building early commercial business cases that guide R&D, BD, and investment decisions.  The role reports to the Vice President, Global Commercial Hematology Franchise Lead.

Essential Functions of the job:

• Create and ensure execution of the insights generation plan that helps inform BeOne understanding of unmet needs, likely evolution in the standard of care, and key stakeholder requirements to drive adoption of emerging therapies. 
• In partnership with the Business Insights (CBDI) team, ensure a comprehensive understanding of the relevant patient segments, marketplace events, competitive landscape, and industry pipeline across the Hematology therapeutic area.  Present key updates as needed to Project and Executive teams.
• In close coordination with Early Development Teams, ensure a comprehensive set of TEPs/TPPs are developed and maintained.  As a best practice, the TEPs/TPPs will be based upon deep customer and competitive insights which guide the development of differentiated assets. 
• Partner with the Pipeline and BD valuation team to quantify the commercial potential of target patient populations as identified within the TEPs/TPPs and ensure full evidence requirements to secure global reimbursement are captured within the TEP/TPP and asset development plans.
• Represent ONE commercial voice to Early Development Teams (EDTs), including the priority early Heme programs. Coordinate with other commercial stakeholders to ensure an integrated, global commercial perspective is included in early asset development decisions.
• Partner with relevant functions to maintain pipeline valuation metrics for the early Hematology portfolio, ensuring any investment decisions are supported by robust commercial assessments and balance BeiGene priorities on risk / return considerations, and speed to the marketplace.
• Collaborate with cross-regional and cross-functional team members to shape disease area strategies for multiple indications, including our overall BeOne pan-Hematology strategy.
• As required, guide commercial decisions regarding early asset positioning, messaging, and branding considerations prior to the formation of Global Product Teams (GPTs).
• In close coordination with cross-functional team members such as Medical Affairs and Corporate Affairs, identify partnership opportunities with Hematology patient organizations and define/execute tactics aligned to the shared agenda of disease education and improving access to efficacious therapies around the globe.
• Lead cross-functional collaboration to ensure alignment of global commercial strategies, including members from R&D, medical affairs, market access and major market organizations.
• Partner with Tech Ops to address any capacity planning considerations.
• Maintain strong relationships with both internal colleagues and external customers to address market opportunities.
• The priority disease areas for this role are AML/MDS, NHL and MPNs and the early hematology development programs.  As business needs warrant, this role may provide support to another Hematology Disease Area / EDT as the BeOne portfolio evolves.

Required Education:

• PhD, PharmD, MA/MS, MBA preferred; BA/BS required

Minimum Qualifications

• BA/BS with 10+ years of experience in pharmaceutical marketing/healthcare-related commercial experience.
• 3+ years of Global Marketing/New Product Planning expertise.
• Previous experience working in Hematology, either at a global level or in-market brand leadership roles.  Demonstrated fluency in the current standard-of-care by key Hematologic Malignancy patient segments and emerging modalities within the industry pipeline. 
• Demonstrated experience in leading brand strategy/new product planning at various stages of lifecycle.
• Strong team player who can incorporate input from key stakeholders (both internally and externally) and drive cross-regional and cross-functional alignment.
• Detailed understanding of opportunity assessment and valuation methodologies deployed within the pharmaceutical industry.
• Proven ability to inspire, motivate and lead matrixed teams.
• Highly skilled and effective in engaging, connecting, and influencing across all levels from senior leadership to local marketing teams.
• Understanding of change management principles and experience driving changes across an organization.
• Strong ability and desire to work across time zones, geographies, and cultures to improve the lives of patients and caregivers.

Preferred Qualifications

• 10+ years of experience in pharmaceutical marketing/healthcare-related commercial experience.
• Demonstrated track record of leading early asset / New Product Planning teams through key R&D governance milestones (e.g Research to Clin Dev, IND, PoC, C2P3, C2FDP).
• Commercial forecasting and/or financial modeling experience.

Computer Skills:   

• PC, including MS Office Suite, MS Teams.   

Travel: 

• ~20–30% for team meetings, KOL/payer research, congresses, and diligence; including international travel.

Location:

• Remote; US-based

Supervisory Responsibilities: 

• This position will not be responsible for management of direct reports.  However, it will require significant cross-functional team leadership and direction of third-party agencies.

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process.  Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact [email protected].