10 Biotech Companies in Charlotte to Know

Charlotte’s biotech companies develop innovative technology products that improve healthcare delivery.

Written by Margo Steines
Published on Jun. 20, 2025
Charlotte at sunset
Photo: Shutterstock
Summary: Charlotte’s biotech scene includes leaders like Dentsply Sirona and Octapharma Plasma, with specialties in connected dentistry and plasma-based therapies. Supported by top research institutions, the region drives innovation in diagnostics, therapeutics and human performance tech.

Charlotte is the largest city by population in North Carolina, where the life sciences industry thrives. The region benefits from the presence of top-tier research institutions including Duke University and UNC Chapel Hill, which provide a strong talent pool. It also benefits from the work of the nonprofit North Carolina Biotechnology Center, an organization that supports local economic development through the commercialization of biotech projects. Charlotte is a contributor to the United States’ global market domination in biotechnology. This list will guide you through the Charlotte biotech scene.

Biotech Companies in Charlotte

  • VALD
  • Diamond Orthopedic
  • Octopharma Plasma
  • Tanner Pharma Group
  • Amissa

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Top Biotech Companies in Charlotte

Pelton & Crane is a dental product company that provides technical equipment for dental offices and surgical suites. In addition to its lines of tools such as cuspidors and chairs, the company also delivers imaging technology. It partners with KaVo to offer dental diagnostic tools for intraoral imaging and cavity detection.

 

Octapharma Plasma operates a large network of plasma donation centers. Headquartered in Charlotte, the company has more than 10,000 employees around the world, working to support its plasma collection and testing services.  This work supports parent company Octapharma AG, which uses human plasma to create therapeutic products based on high-quality human proteins.

 

Tanner Pharma Group is a business consultancy that works with the biotechnology and pharmaceutical sectors to establish equitable access to medications. Its global service offerings support areas including international commercialization, clinical trial enrollment and global access programs, with the goal of bringing lifesaving treatments to underserved populations.

 

Point B is a consulting firm that works within the biotech sector to offer strategic guidance in business processes and technology. The goal of this work is to accelerate time-to-market for life-changing treatments. The company’s areas of focus include therapeutic portfolio management, clinical acceleration and implementing AI across product design processes. 

 

The dental technology company Dentsply Sirona offers a full suite of dental tools and products, with an emphasis on “connected dentistry.” This treatment approach relies on software tools and sensor-equipped hardware to provide real-time data during procedures. The company’s products include dental implant solutions and restorative materials for crowns and fillings.

 

Eli Lilly and Company is a pharma and biotech company that has been active in the healthcare industry since 1876. It researches, develops and manufactures biotechnology products at its in-house facilities, and the company recently partnered with Creyon Bio on a $1 billion deal to create an AI-powered drug discovery tool.

 

Sonablate enables minimally invasive procedures through its high-intensity focused ultrasound, or HIFU, technology. Applications for HIFU include treating localized prostate cancer and other tumors that take solid form within specific human organs. HIFU is also used in cosmetic procedures to improve skin quality and appearance. The Sonablate HIFU relies on intra-treatment ultrasound-guided imaging for safety and precision.

 

VALD is a biotech company that works with musculoskeletal health metrics. It offers a large suite of products for kinesthetic optimization, such as the NordBord hamstring testing system and the HumanTrak movement analysis system. It bills its offerings as “technology for human performance,” and it builds them to support physical therapy and performance athletics.

 

Diamond Orthopedic develops solutions for orthopedic fixation. This category of procedure treats bone fractures by securing anatomy with mechanical parts like rods, plates and screws, which hold bones in place while they heal. Diamond Orthopedics specializes in producing faceted thread form bone screws, for which it holds a patent.

 

Amissa is a medical IoT company that makes technology to track health metrics through wearable devices. The company focuses on cognitive health, with specialties in women’s midlife cognitive health and dementia. The Amissa platform integrates with the Apple Watch and delivers clear insights on biometric data and on subjective symptom tracking.

 

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